MBMR Biolabs portfolio offers some of the most cutting-edge products in bio-orthogonal chemistry.
The inverse-electron demand Diels Alder cycloaddition (tetrazine cycloaddition) between trans-cyclooctenes and tetrazines is biocompatible and exceptionally fast. A variety of applications has been developed that utilize tetrazine cycloaddition to image and retrieve nucleic acids, proteins, glycans, lipids, and other metabolites in vitro, in cells as well as in whole organisms. By tagging these biomolecules, researchers can monitor their dynamics in living systems and discover specific substrates of cellular pathways. Additionally, tetrazine conjugation has allowed development of novel diagnostic tools, including radiochemical labeling of macromolecules for pretargeted SPECT/CT imaging of tumors in live mice.
We aim to provide comprehensive solutions that will enable researchers of diverse scientific disciplines to utilize tetrazine bioconjugation in their work. We thank you for your interest in our company and invite you to collaborate with us.
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